产品货号：
Z10658
中文名称：
ALDH2抗体
英文名称：
Anti-ALDH2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ALDH2 Antibody |
| 指标别名 | ALDH class 2;ALDH E2;ALDH2;ALDHI;ALDM |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | ALDH2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human ALDH2 (18-48aa SAAATQAVPAPNQQPEVFCNQIFINNEWHDA),different from the related mouse sequence by two amino acids,and from the related rat sequence by one amino acid. |
| 实际分子量 | 56KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ALDH2 (Aldehyde Dehydrogenase 2 Family) is a human gene.The enzyme encoded by this gene belongs to the aldehyde dehydrogenase family of enzymes that catalyze the chemical transformation from acetaldehyde to acetic acid.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Hsu et al.(1985) assigned the ALDH2 locus to chromosome 12 by means of a cDNA probe and Southern blot analysis of somatic cell hybrids.Using an unbiased proteomic search,Chen et al.(2008) identified mitochondrial ALDH2 as an enzyme whose activation correlated with reduced ischemic heart damage in rodent models.A high-throughput screen identified a small molecule activator of ALDH2,which they called Alda-1,that,when administered to rats before an ischemic event,reduced infarct size by 60%,most likely through its inhibitory effect on the formation of cytotoxic aldehydes. |
| Uniprot ID | P05091 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | aldehyde dehydrogenase 2 family (mitochondrial) |
| 蛋白名全称 | Aldehyde dehydrogenase,mitochondrial |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：ALDH2抗体，ALDH2多抗，Anti-ALDH2 Antibody